CSIR-IICT Synthesis for COVAXIN agonist molecule.

CSIR-IICT Synthesis for COVAXIN agonist molecule.

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Constituent laboratories of the Council of Scientific and Industrial Research (CSIR) have continuously been cooperating with industry on the establishment and conduct of clinical studies to launch repurposes of medicaments. CSIR labs has participated significantly in the development of SARS-CoV-2 screening diagnostic kits, including Feluda and Dry Swab Direct RT-PCR.
The Hyderabad-based Bharat-Biotech indigenous vaccine for COVID-19, COVAXIN is a heavily cleansed, entirely virion, inactivated SARS-CoV2. Algel-IMDG, contained in the aluminium hydroxide gel chemisorbed agonist TLR7/8, has been developed as the required form of the immune response.

Dr Chandrasekhar, director, and Dr Raji Reddy, senior scientist from the company led the project.
In a record period of four months, the IICT was finished. CSIR-IICT has played a leading role in developing analytical methods of measuring TLR7/8 molecule and methods validation process through National Accreditation Board of Testing and Calibration Laboratories (NABL) under Dr Mohana Krishna Mudiam, Senior Principal Scientist, Professor Academy of Scientific and Innovative Research (AcSIR).
The project was led in a record period of 4 months by Dr Chandrasekhar, the Director and Dr. Raji Reddy, the IICT Senior Scientist. CSIR-IICT also covers the Senior Scientist and Professor of the Sciences and Innovative Research Academy Dr Mohana Krishna Mudiam.

The development of a research tool for the TLR7/8 Agonist (AcCSIR) played a major role.Molecular process and method of certification by means of the National Testing Accreditation Board.Accredited laboratory Calibration Laboratories (NABL).
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